TDP-43 Proteinopathies
TDP-43 Proteinopathies: Understanding the Impact and Management 1. Introduction TDP-43 proteinopathies refer to a group of neurodegenerative disorders characterized by the abnormal accumulation of TDP-43 protein in the nerve cells of the brain and spinal cord. This protein plays a crucial role in RNA processing and regulation of gene expression within cells. When TDP-43 protein…