Polymyxin B Sulfate and Trimethoprim (POLYMYXIN B SULFATE AND TRIMETHOPRIM SULFATE) by A-S Medication Solutions
INDICATIONS AND USAGE
Polymyxin B Sulfate and Trimethoprim ophthalmic solution is indicated for the treatment of surface ocular bacterial infections, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following organisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae, and Moraxella (Branhamella) catarrhalis.
DOSAGE AND ADMINISTRATION
In mild to moderate infections, instill one drop in the affected eye(s) every 3 hours (maximum of 6 doses per day) for a period of 7 to 10 days.
Administration Instructions
– Tilt the head back and pull down the lower eyelid to create a small pocket.
– Hold the dropper above the eye and squeeze out a drop.
– Close the eye for 1 to 2 minutes with gentle pressure on the inside corner of the eye.
Dosage Adjustment
No dosage adjustment is necessary in patients with renal impairment.
Missed Dose
If a dose is missed, it should be administered as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule resumed.
Storage
Store at 15°C to 25°C (59°F to 77°F). Protect from light.
PRECAUTIONS
General
– Polymyxin B Sulfate and Trimethoprim ophthalmic solution is not for injection.
– Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi.
Information for Patients
Patients should be advised not to touch the dropper tip to any surface to avoid contamination.
Use with Contact Lenses
Contact lenses should be removed prior to instillation of the ophthalmic solution. Lenses may be reinserted 15 minutes following administration.
ADVERSE REACTIONS
The most frequent adverse reactions to Polymyxin B Sulfate and Trimethoprim ophthalmic solution are localized allergic reactions, including itching, swelling, and conjunctival erythema.
FAQ
Q: How often should I use Polymyxin B Sulfate and Trimethoprim ophthalmic solution?
A: In mild to moderate infections, instill one drop in the affected eye(s) every 3 hours (maximum of 6 doses per day) for a period of 7 to 10 days.
Q: Can I use Polymyxin B Sulfate and Trimethoprim ophthalmic solution with contact lenses?
A: Contact lenses should be removed prior to instillation of the ophthalmic solution. Lenses may be reinserted 15 minutes following administration.
Q: What should I do if I miss a dose of Polymyxin B Sulfate and Trimethoprim ophthalmic solution?
A: If a dose is missed, it should be administered as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule resumed.
Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a healthcare professional before making any decisions about your health or medication.
